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ABOUT US | OUR VISION | PRODUCTS | MARKET SERVED | CUSTOMER RESPONSE | TECH INFO | MSDS INFO | SAFETY INFO | FEEDBACK | CONTACT INFO |
| Product Name: | Nitrous Oxide |
| Chemical Name: | Nitrous Oxide |
| Formula: | N2O | 0 |
| Chemical Family: | Oxidizer | 2 | 0 |
| Use: | Medical, industrial, food industry | OX |
| Synonyms: | Dinitrogen monoxide, laughing gas, nitrogen monoxide, nitrous oxide USP |
| ¨ ¨ |
| NFPA Fire: | 0 | HMIS Fire: | 0 | Acute: | Yes |
| NFPA Health: | 2 | HMIS Health: | 2 | Chronic: | Yes |
| NFPA Reactivity: | 0 | HMIS Reactivity: | 0 | Fire: | Yes |
| NFPA Special Hazard: | OX | Mixture: | No | Reactive: | No |
| Sudden Release Pressure: | Yes |
| 02. INGREDIENTS - COMPOSITION & INFORMATION |
| PERCENT | EXPOSURE GUIDELINES |
| COMPONENT | CAS No. | (BY WT.) | OSHA - TWA | ACGIH - STEL |
| Nitrous Oxide | 10024-97-2 | 99.0% | 100.0% | None. | 50ppm |
| LD50: None. LC50: None. | Note: NIOSH has recommended a TWA of 25 ppm during |
| anesthetic administration, and 50 ppm in dental offices. |
| 03. HAZARDS IDENTIFICATION |
| EMERGENCY OVERVIEW: |
| Warning: | High pressure oxidizing liquid and gas. |
| Vigorously accelerates combustion. |
| Can cause rapid suffocation. |
| Can cause anesthetic effects. |
| May cause frostbite. |
| Potential Health Effects Information: |
| Routes of Exposure: |
| Inhalation: | Simple asphyxiant. Nitrous oxide is nontoxic, but may cause suffocation by |
| displacing the oxygen in air. Exposure to oxygen-deficient atmosphere (<19.5%) |
| may cause dizziness, drowsiness, nausea, vomiting, excess salivation, diminished |
| mental alertness, loss of consciousness and death. Exposure to atmospheres |
| containing 8-10% or less oxygen will bring about unconsciousness without warning |
| and so quickly that the individuals cannot help or protect themselves. Lack of |
| sufficient oxygen may cause serious injury or death. |
| Exposure to concentrations of 50% or greater will produce euphoria, loss of |
| coordination, slurred speech, dulling of senses, loss of consciousness, and clinical |
| anesthesia. These symptoms may resemble intoxication, hence the name "laughing |
| gas". At higher concentrations, approaching 100%, inhalation may cause deep |
| breathing, dizziness, nausea, and central nervous system depression. |
| WARNING: The misuse of nitrous oxide can cause death by reducing the amount |
| of oxygen necessary to support life. Nitrous oxide abuse can impair an individual's |
| ability to make and implement life sustaining decisions. |
| Eye Contact: | Contact with liquid or cold vapor can cause freezing of tissue. |
| Skin Contact: | Contact with liquid or cold vapor can cause frostbite. |
| Chronic Effects: | Nitrous oxide has been associated with several effects from long term exposure. |
| The most strongly substantiated effect is neuropathy (degenerative changes to the |
| nervous system). Complaints include numbness, tingling of hands and legs, loss of |
| feeling in fingers, poor balance, and muscular weakness. Epidemiological studies |
| also suggest feto-toxic effects and higher incidents of spontaneous abortion in |
| exposed personnel. Although no cause and effect relationship has been firmly |
| established, exposure to the gas should be minimized. |
| Medical Conditions Aggravated By | Pregnant women should avoid exposure to nitrous oxide. See Section 11 |
| Overexposure: | "Toxicological Information" |
| Other Effects Of Overexposure | See Section 11 "Toxicological Information". |
| Carcinogenicity: | Nitrous oxide is not listed by NTP, OSHA or IARC. |
| 04. FIRST AID MEASURES |
| Inhalation: | Persons suffering from lack of oxygen should be removed to fresh air. If victim is |
| not breathing, administer artificial respiration. Vomiting may occur as the person |
| awakes. In order to prevent aspiration, exposed individuals should be placed on |
| their side with their head at the level or slightly lower than their body. If breathing is |
| difficult, or dulling of senses is present, administer oxygen. Obtain prompt medical |
| attention. |
| Rescue personnel should be aware of the extreme fire hazards associated with |
| oxidizer-enriched atmospheres. |
| Eye: | Contact with liquid or cold vapor can cause freezing of tissue. Gently flush eyes |
| with lukewarm water. Obtain medical attention immediately. |
| Skin: | Contact with liquid or cold vapor can cause frostbite. Immediately warm affected |
| area with lukewarm water not to exceed 105°F (40°C). |
| Ingestion: | None. |
| Note To Physician: | Nitrous oxide may suppress immunological function when administered for |
| anesthetic purposes. This may reduce the resistance to infection and other |
| immuno-dependent disease processes. Nitrous oxide may cause vitamin B-12 |
| deficiency. Megaloblastic anemia and nervous system disorders can occur as a |
| result of this chemically induced deficiency. More detailed information can be found |
| in Section 11 "Toxicological Information". |
| 05. FIRE FIGHTING MEASURES |
| Flash Point: | Not applicable; Gas. |
| Auto ignition: | Nonflammable. |
| Flammable Limits - Lower: | Not applicable. |
| Flammable Limits - Upper: | Not applicable. |
| Extinguishing Media: | Nitrous oxide is nonflammable and will support combustion. Use extinguishing |
| media appropriate for the surrounding fire. |
| Fire Fighting Instructions: | Evacuate all personnel from the danger area. If possible, shut off flow of nitrous |
| oxide which is supporting the fire. Immediately cool containers with water spray |
| from maximum distance. When cool, move containers from fire area, if without |
| risk. |
| Fire And Explosion Hazards: | Oxidizing agent, vigorously accelerates combustion. Some materials which are |
| noncombustible in air will burn in the presence of an oxidizing agent. Nitrous oxide |
| may form explosive compounds when exposed to combustible materials or oil, |
| grease, and other hydrocarbon materials. |
| Upon exposure to intense heat or flame, cylinder will vent rapidly and/or rupture |
| violently. Most cylinders are designed to vent contents when exposed to elevated |
| temperatures. |
| Pressure in a container can build up due to heat and it may rupture if pressure relief |
| devices should fail to function. |
| Hazardous Combustion Products: | None known. |
| Sensitivity To Static Discharge: | Not applicable. |
| Sensitivity To Mechanical Impact: | None. |
| 06. ACCIDENTAL RELEASE MEASURES |
| Steps to be taken is material is released | Evacuate all unnecessary personnel from the affected area. Shut off source of |
| or spilled: | nitrous oxide, if possible. Remove sources of heat, ignition and, if possible, separate |
| combustibles from the leak. |
| Ventilate enclosed area or move leaking container to a well-ventilated area. If |
| leaking from cylinder or its valve, contact your supplier. |
| 07. HANDLING AND STORAGE |
| Storage: | Store and use with adequate ventilation. Cylinders should be separated from |
| flammables by a minimum distance of 20 ft. or by a barrier of non-combustible |
| material at least 5 ft high having a fire resistance rating of a least 1/2 hour. |
| Cylinders should be stored upright with valve protection cap in place and firmly |
| secured to prevent falling or being knocked over. Post "No Smoking or Open |
| Flames" signs in the storage area. Protect cylinders from physical damage; do not |
| drag, roll, slide or drop. Do not allow storage area temperature to exceed 125°F |
| (52°C). Full and empty cylinders should be segregated. Use a first-in, first-out |
| inventory system to prevent full containers from being stored for long periods of |
| time. |
| Because of its "laughing gas" anesthetic effect, nitrous oxide is often subject to theft |
| and misuse. Cylinders should be stored and used in a controlled area. |
| Handling: | Use a suitable hand truck for cylinder movement. Never attempt to lift a cylinder |
| by its valve protection cap. Keep cylinders and their valves free from oil and |
| grease. Open valve slowly. If user experiences difficulty operating cylinder valve, |
| discontinue use and contact supplier. Never insert an object (e.g., wrench, |
| screwdriver, pry bar, etc.) into valve cap openings. Doing so may damage valve, |
| causing a leak to occur. Never strike an arc on a compressed gas cylinder or make |
| a cylinder a part of an electrical circuit. Use an adjustable strap wrench to remove |
| over-tight or rusted caps. For additional precautions in using nitrous oxide see |
| Section 16 - Other Information. |
| 08. EXPOSURE CONTROLS - PERSONAL PROTECTION |
| Engineering Controls: |
| Ventilation: | Natural or mechanical to prevent accumulation in worker's breathing zone above |
| exposure limits. (See Section 2). |
| Personal Protective Equipment (PPE): |
| Glasses: | Safety glasses are recommended when handling cylinders. |
| Shoes: | Safety shoes are recommended when handling cylinders. |
| Gloves: | Work gloves are recommended when handling cylinders. If used, gloves must be |
| clean and free of oil and grease. |
| Respirator: | None required in general use. |
| Emergency Use: | Self-contained breathing apparatus (SCBA) or positive pressure airline with mask |
| are to be used in oxygen-deficient atmosphere. Respirators will not function. |
| 09. PHYSICAL AND CHEMICAL PROPERTIES |
| Physical State: | Gas |
| Color: | Colorless |
| Odor: | Slightly sweet |
| Molecular Weight: | 44.013 |
| Boiling Point: | -127.4°F ( -88.5°C) @ 1 atm |
| Specific Gravity: | 1.53 At 70°F (21.1°C) @ 1 atm, Air = 1 |
| Freezing/Melting Point: | -131.5°F (-90.8°C) at 1 atm |
| Vapor Pressure: | 745 psig at 70°F |
| Vapor Density: | .1146 lb./cu ft (1.947kg/CuM), At 70°F (21.1°C) @ 1 atm |
| Water Solubility: | 1.3 Vol./Vol. At 32° F (0°C) |
| Expansion Ratio: | Not Applicable - Gas |
| pH: | Not Applicable - Gas |
| Odor Threshold: | None Known |
| Evaporation Rate: | Not Applicable - Gas |
| Coefficient Of Water/Oil Distribution: | Information not available |
| 10. STABILITY AND REACTIVITY |
| Chemical Stability: | Stable |
| Incompatibility With Other Materials: | Flammable materials, hydrocarbons such as oils and grease, asphalt, ethers, alcohols, |
| acids and aldehydes. Alkali metals, boron, tungsten carbide, and aluminum. |
| Hazardous Decomposition Products: | Nitrogen and oxygen. |
| Hazardous Polymerization: | Will not occur |
| 11. TOXICOLOGICAL INFORMATION |
| Other Studies Relevant To Material: | Exposure to nitrous oxide has produced embryofetal toxicity in animals as evidenced |
| by reduced fetal weight, delayed ossification, and increased incidence of visceral |
| and skeletal variations. Exposure may be associated with increased incidence of |
| abortion in humans. Single prolonged exposure to high concentrations of nitrous |
| oxide has resulted in bone marrow injury and adverse effects in blood. |
| Irritancy Of Material: | None. |
| Reproductive Effects: | None. |
| Teratogenicity: | None. |
| Synergistic Materials: | None. |
| Sensitization To Material: | None. |
| Mutagenicity: | None. |
| 12. ECOLOGICAL INFORMATION |
| ECOTOXICITY: | No adverse ecological effects are expected. Nitrous oxide does not contain any |
| Class I or Class II Ozone depleting chemicals (40 CFR Part 82). Nitrous oxide is |
| not listed as a marine pollutant by DOT (49 CFR Part 171). |
| 13. DISPOSAL CONSIDERATIONS |
| Waste Disposal Method: | Do not attempt to dispose of residual or unused quantities. Return cylinder to |
| supplier. |
| For emergency disposal, discharge slowly to the atmosphere in a well ventilated |
| area or outdoors away from all sources of ignition. |
| 14. TRANSPORT INFORMATION |
| DOT/IMO Shipping Name: | Nitrous oxide |
| Hazard Class: | 2.2 (Non Flammable gas.) |
| Identification Number: | UN 1070 |
| PIN: | 1070 |
| Product RQ: | None. |
| Shipping Label: | Nonflammable Gas and Oxidizer. |
| Placard (When Required): | Nonflammable Gas. |
| Special Shipping Information: | Cylinders should be transported in a secure position, in a well ventilated vehicle. |
| The transportation of compressed gas cylinders in automobiles or in closed-body |
| vehicles can present serious hazards and should be discouraged. |
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